Thursday, October 17, 2019
The importance of iron in the human body Essay Example | Topics and Well Written Essays - 1250 words
The importance of iron in the human body - Essay Example Deficiency of iron is found to affect the normal functioning of the human body in several ways indicating the importance of iron to the human body. This requirement varies based on age and gender. (1). Iron is an important element for the normal functioning of the human body The Importance of Iron to the Human Body Among the many metals found in the earthââ¬â¢s crust iron is the second most abundant metal. During the course of evolution of living organisms iron became a key metal for the existence of living organisms and this is reflected in the importance of iron to the human body. Many of the functions in the human body at the cell level find iron playing a significant. In the human body normally about 50mg per kilogram of body weight is the quantum of iron present. On an average this works out to between 3-4gms in a human adult. Of this amount of iron in the human body approximately 60% is present in the form of hemoglobin in the erythrocytes. Nearly ten percent of iron present in the human body is found in myoglobin in the muscle. Iron containing proteins like cytochromes, iron-sulphide enzymes and iron storage and transporting proteins is where the remaining 30% of the iron on the human body can be found. This shows that iron is not present in the body as free ions in the body fluids or tissues. (2). Taken at glance the main functions of iron in the human body consists of DNA synthesis and cell formation; sensing of oxygen and cellular uptake of oxygen, transportation and storage of oxygen within the blood and muscles; electron transfer and conversion of oxygen to adenosine triphosphate (ATP); antioxidant as well as pro-oxidant functions; and regulation of inter-cellular iron. The many functions of iron in the human is the reason that iron is present in the human body in its functional forms rather than as free ions in the body fluids and tissues. (3). Hemoglobin Iron is essential as a cofactor in the formation of red blood cells and hemoglobin and it i s a part of the structure of hemoglobin. Hemoglobin makes up most of the cytoplasm of erythrocytes. Each molecule is made up of four protein or globin chains, which is attached to prosthetic heme group. The heme group has an iron molecule that is complexed at the centre of a porphyrin ring. Hemoglobin is very efficient at binding and carrying oxygen. This efficiency is reflected in its ability to causer blood to carry almost hundred times the oxygen in comparison to plasma alone. An added factor in this ability of hemoglobin to act as the transporter of oxygen in the human body is the capability of hemoglobin to modulate oxygen binding under different conditions. This feature of hemoglobin permits adaptation to a wide variety of environments and demands within the human body. When there is a deficiency of iron normal erythrocyte and hemoglobin production in the human body is affected. The lack of iron causes a reduction in the synthesis of the heme group, which gets translated into effects on the globin production. The reduced presence of the heme group in the red blood cells make the cells smaller and gives them a paler appearance than red blood cells produced that are produced when adequate levels of iron are present. In the presence of adequate levels of iron the maturing red blood cells continue dividing as per their development program till such time as the hemoglobin gas attained appropriate levels. When iron is not present in adequate levels the
Unit 3 DB Acct310 Essay Example | Topics and Well Written Essays - 250 words
Unit 3 DB Acct310 - Essay Example rder costing system is mainly used in service industries including hospitals, movie studios, law firms and even repair shops as well as in cases where individual non-homogeneous goods are produced by an organization. When it comes to this type of system, record keeping and cost problems can be very complex to handle especially where different products and services are available, compared to when dealing with single products and services. Since the products available are different, the cost will relatively be different hence a cost record for each product. Therefore, job order costing needs a lot of effort and concentration as compared to process costing system. Process costing involves tracing and accumulation of direct costs, and the allocation of indirect costs of manufacturing processes (Hansen & Mowen, 2006). Process costing is much applicable when the products in question are naturally homogeneous. Costs are in this case assigned to products which are produced en mass as noted by Hansen and Mowen (2006). This method is mostly suitable for industries such as chemical manufacturing companies since the process flow is continuous. In this system a production report is prepared to summarize the totals and cost of units. In the case of a company that deals with chemicals, cement, electrical parts, textiles and pharmaceuticals products, process costing method is advisable. This is because their production process is continuous and order costing method may not be appropriate for this kind of companies. Job order costing is applicable in companies that manufacture many different products for example clothing factory and service industries (Hansen & Mowen, 2006). Each product has its own price hence this system is appropriate to use and follow. Records of each and every order and its cost are stored separately for easy understanding and follow up. Records in a process order costing system are much easier to follow and less complicated as compared to job order
Wednesday, October 16, 2019
German Essay Example | Topics and Well Written Essays - 250 words - 1
German - Essay Example There are also memorials dedicated to other victims (Gypsies, homosexuals) in Berlin as well as in other places of the world. The latter are smaller in size. However, this is quite inappropriate, as it may seem that the lives of Jews are valued higher than the lives of other victims. It is better to create one memorial where all victims could be mentioned. It could be a good idea to have a memorial where signs worn by people (stars, triangles and so on) could be revealed as well as the number of people who died. Another point is that the memorial seems to commemorate victims who died in the concentration camps. However, there were survivors whose lives were completely destroyed. Memorials should also commemorate lost lives of those people. It seems more appropriate to make the memorial for victims of the Holocaust rather than for murdered Jews of Europe. It is also quite interesting that there is a Holocaust Museum in Washington, but no national monument for victims of slavery and genocide. This may be explained by the fact that there are many people who have enough power and who strive for commemorating the killed Jews (whose relatives and children live in the USA) and there are a few people, who also have certain power, and are willing to commemorate slavery or
Tuesday, October 15, 2019
Unit 3 DB Acct310 Essay Example | Topics and Well Written Essays - 250 words
Unit 3 DB Acct310 - Essay Example rder costing system is mainly used in service industries including hospitals, movie studios, law firms and even repair shops as well as in cases where individual non-homogeneous goods are produced by an organization. When it comes to this type of system, record keeping and cost problems can be very complex to handle especially where different products and services are available, compared to when dealing with single products and services. Since the products available are different, the cost will relatively be different hence a cost record for each product. Therefore, job order costing needs a lot of effort and concentration as compared to process costing system. Process costing involves tracing and accumulation of direct costs, and the allocation of indirect costs of manufacturing processes (Hansen & Mowen, 2006). Process costing is much applicable when the products in question are naturally homogeneous. Costs are in this case assigned to products which are produced en mass as noted by Hansen and Mowen (2006). This method is mostly suitable for industries such as chemical manufacturing companies since the process flow is continuous. In this system a production report is prepared to summarize the totals and cost of units. In the case of a company that deals with chemicals, cement, electrical parts, textiles and pharmaceuticals products, process costing method is advisable. This is because their production process is continuous and order costing method may not be appropriate for this kind of companies. Job order costing is applicable in companies that manufacture many different products for example clothing factory and service industries (Hansen & Mowen, 2006). Each product has its own price hence this system is appropriate to use and follow. Records of each and every order and its cost are stored separately for easy understanding and follow up. Records in a process order costing system are much easier to follow and less complicated as compared to job order
Hume and his contemporaries Essay Example for Free
Hume and his contemporaries Essay Live art performances, marked by an overture of spirituality, consciousness, physical introductions to pain, drawn further on to include specific rituals, symbolisms, varied states of emotions brought by self-inflicted hurt and eventually, culminating in a wild display of frenzy and shocking images, are less likely to please the uninitiated audience than it will provoke a sense of awe and wonderment among performance art critics. In a similar situation, Marina Abramovicââ¬â¢s attempts to upend the static discourses of physicality, mental states of mind and art that pervade current Western hegemony, understandably, can only be regarded in the extremes by people steeped firmly into formal traditions. Either her method of performance will elevate its spectators to a heightened degree of appreciation, therefore merit a thunderous welcome to a novel brand, sui generis, of art of our time at the end of each scene; or her gruesome didactics on the bodyââ¬â¢s threshold for pain, simply fails to pass muster. Her performance practice, a risk more than anything else, certainly inspire debates on whether or not to set moral, perhaps even social limits to art in order to determine, in precise and concrete terms, at which point creativity and imaginative art themes and performances become either delightful to the senses or noxious to the sensitivities of the general public. The idea of drawing the line along and between different shades of extremes, although already evinced clearly in the works of Marina Abramovic, seems to fit the consensus on the idea of censuring the bold and burlesque, stripping it off its material enunciation and expression to mitigate the horror and revulsion inherent in the exposition, or in the worst case, totally ignore it until the novel yet misunderstood facade fades from inattention. However, thanks mainly to Marina Abramovicââ¬â¢s unwavering desire to reach her audience, despite the sometimes hostile reception during her performances itself, in ways that continually push the envelope of spectator tolerance, did she carry her work from the esoteric art circles to mainstream. To wit, in one of her collaborative performances with Ulay, entitled Incision (1978), while purposively eliciting reaction, probably direct participation, from their audience, one of the spectators primed the climactic resonance of the work by jumping into the stage to kick Marina Abramovic as she was lying prostate right in the middle of the act. In her biographical work, she writes that although she expected the attack to happen any moment during the performance, she did not realize the immediacy and steeled resolution of that man who assailed her (Abramovic, 1998). Photographs of the show caught the man with a leg lifted, jumping into the air. ââ¬Å"The next photograph shows Abramovic lying on the floor, and the man seems to be landing from a kicking action [â⬠¦] the audiences interrogation manifested in a spontaneous physical attack (Tang, 2005). Ethical and moral questions, as well as aesthetic controversies have been discussed quite animatedly as early as the 18th century. Philosophers, like David Hume, have started to addressed the tough issues about morality, art and tasteââ¬âthe chief concerns that pervaded his era. Cynthia Freeland, introducing the notions of Taste and Beauty, in a book about defining the slippery strands of art, writes that Hume and his contemporaries ââ¬Å"would not have approved of blasphemy, immorality, sex, or the use of body fluids as appropriate in artâ⬠(Freeland 2001). As a caveat to this general statement, it must be understood that even though 18th century consciousness all the way up to the present have not been too open in giving cognizance to art that smack of Marina Abramovicââ¬â¢s own brand of carnal art expressions, there are already extant cultural and social systems which places importance into shamanistic and ritualistic gestures. Among art critics and historians, some pursue a theory of art as ritual: ââ¬Å"ordinary objects or acts acquire symbolic significance through incorporation into a shared belief systemâ⬠(Freeland, 2001). In the same vein, Freeland further digs deep in history to provide evidence in varied cultural rituals that depict blood and physical pain. She avers that ââ¬Å"when a Mayan king shed blood before the multitude in Palenque by piercing his own penis and drawing a thin reed through it three times, he exhibited his shamanistic ability to contact the land of the undeadâ⬠(2001). Other modern artists try to recreate a similar sense of art as ritual, just as much as Marina Abramovic has had for the last three decades. Diamanda Galas, for instance, ââ¬Å"fuses operatic wizardry, light shows and glistening blood in her Plague Massâ⬠(2001), supposedly to exorcise pain in the era of Aids. Herman Nitsch, Viennese founder of the Orgies Mystery Theater, promises ââ¬Å"catharsis through a combination of music, painting, wine-pressing, and ceremonial pouring of animal blood and entrailsâ⬠(Nitsch, n. d. in Freeland, 2001). As it turns out, these very rituals are ingrained in Western traditions. Illuminating examples of which are the amount of blood depicted in Europeanââ¬â¢s, and verily much of the cultures in the modern world today, two main belief discourses: that of the Judeo-Christian and the Greco-Roman. By taking a cursory review of religious and classical texts of Western traditions, we are able to immediately uncover a plenitude of blood representations and ritualistic sacrifices. In the Old Testament, Yahweh is seen to require ââ¬Å"sacrifices as parts of His covenant with the Hebrewsâ⬠(Freeland, 2001). Similarly, Agamemnon ââ¬Å"faced a divine command to slit the throat of his own child [â⬠¦] the blood of Jesus is so sacred that it is symbolically drunk to this day by believing Christians as promising redemption and eternal lifeâ⬠(2001). Such myths and religious stories are rather germane to Western art. We read of Homeric heroes wining the favors of their gods and goddesses by sacrificing animals. Likewise, the tragedies of Lucan and Seneca ââ¬Å"piled up more body parts than Freddy Krueger in A Nightmare on Elm Sreetâ⬠(2001). Not surprisingly, likewise, Renaissance paintings are never without a hint of blood draped at the canvassed in hard red-acrylic paint whilst Shakespeareââ¬â¢s tragedies typically concluded with swordplay and stabbings. The preceding examples of ritualistic performances which involves blood and sacrifices, death and disease, murder and trials, are very instructive with regards to our penchant for the macabre and the dreadful. It is in these premises that Marina Abramovic draws much of her inspiration to create an art, pro forma, that bespeak of our capacity to endure scenes of gore and violenceââ¬âif only on a less exacerbated state. Her performance, for the most part, certainly places importance on the symbolic values of ceremonies, gestures and artifacts. Albeit appearing random and spontaneous, her methods establish a logical connection between her consciousness while performing and her bodyââ¬â¢s means of coping with the strength of self-infliction. In the nascent days of her art, she has performed controversial after controversial explorations into the limitations of the mind and the body. Rhythm 10, in 1973, was the first in a series of abject surrender to the inevitability of suffering. Alone in the stage, she prepared a set of knives to be used as piercing objects in a risky game of Russian hand roulette. Without signs of hesitation, she proceeded to stab the spaces between her fingers in a rough yet determined fashion. Each time she made the mistake of cutting her flesh; she dropped the knife and took out another one to repeat the process all over again until she made use of all ten knives (Abramovic, 1998). The following year, in the performance entitled Rhythm 5, she sought to re-evoke the energy of extreme body pain by constructing a huge star soused with combustible petroleum liquid. At the onset, the structure as lit to flames, and while she was standing right outside the contraption, she religiously clipped her fingernails, cut her hair and them inside the burning star. The denouement of the program was when she danced around and then flew across the flames into the center of the burning star. Serious and life-threatening complications ensued when the smoke that engulfed her from inside asphyxiated her to the point that she no longer had control of her actions. The medical team and the audience, who were all there to watch, started to suspect that something was terribly amiss. Fortunately, the quick responses from the stand-by technicians saved her from an untimely death caused by severe smoke inhalation (Abramovic, 1998). In the same year and the years that followed, Marina Abramovic designed similar art experiments that were meant to test the limits of herself and her body, and later the audience and their tolerance for vicarious agony through her body. Rhythm 2 and Rhythm 0, were performed with the hopes of proving that the consciousness can go beyond the rubric of psychological triggers in mind. The sole aim of both was to uproot the inherited tendencies of the mind to reel from stark images and provocative gestures. She sought to cultivate in the audience a sense of indifference in order that one may reach a virtual catharsis what with all the sharp and strong representations between the body and suffering. For artists like Marina Abramovic, it is clear to them that what they are performing, and while in the act of performing, there is a higher purpose that they wish to achieve regardless of the methods by which these are made possible. They have a firm understanding and appreciation for every act and gesture that they make. None of such are done without rhyme and reason. For artists like Marina Abramovic, everything that happens during any performance, in spite of the harsh opinions of critic that meet them right afterwards, makes a lot of sense. However, audiences who see and react to these artists do not enter, much less share the beliefs and values, or with prior knowledge of what will transpire, with that of the artist. When asked about the origins of her creativity and ideas for her art performance, Marina Abramovic happily recalls her childhood memories with her parents. As if to show indeed that her style was a result of previous life experiences that may be susceptible to a psychoanalytical reading, she narrates: ââ¬Å"A long time ago I made a piece called Art Must Be Beautiful, Artist Must Be Beautiful. At that time, I thought that art should be disturbing rather than beautiful. [â⬠¦]My life is full of such contradictions. [â⬠¦] My father and mother are divorced. As an adult, I recently wanted to go back to help them because of the war. With the embargo, there is nothing in the stores. [â⬠¦] I called my father to ask him what he needs, and he dictates a long list antibiotics, bandages, penicillin, toilet paper, coffee, sugar, powdered milk, all these basic things for survival. Then I call my mother and ask what she needs. She says, I need Chanel lipstick, Absolute Red, Number 345, and hair spray. I am between these two. â⬠(Abramovic, 2005) Most modern art, in this case, within the context of theatre, videos and live performances, fail to provide ample background reinforcement against the dominant traditions and systems of belief. What invariably happens is that the audiences will remain ignorant to, consequently, unappreciative of the complexities and undertones of the supposedly artful, meaningful and profound gestures. The audience, instead of sharing that same degree of catharsis, sacrifice and initiation, will shy away. They themselves are alienated from the performance so much that they are brought far afield the community, forcing them to abandon the art because of pure shock and horror, largely as a result of their ineligibility to feel as the artists do (Freeland, 2001). Damien Hirst, the ââ¬ËBritpackââ¬â¢ artist who sparked controversy in the 1990s with his motley display of macabre high-tech exhibits of ââ¬Å"dead sharks, sliced cows, or lambs in glasses of formaldehyde, [â⬠¦] has parlayed his notoriety into success with his popular Pharmacy restaurant in Londonâ⬠(Freeland, 2001). By no means, therefore, are the works that revolve around symbolisms, spirituality, humanity and fatalism seldom reflects the nature of most of our ritualistic traditions. Symbols of pain and suffering that are central to many religions, cultural systems, political and social units, may come off to the lay person as undesirable and may even cause the same panic as had the man in Marina Abramovicââ¬â¢s performance. Art performance that utilizes imageries that hint at violence, torture and distress, when it is performed in the public who has no inkling of its context, meaning and history are in danger of misconstruing art for capricious display of filth and tripe. As with all in theatre, the performer must work against mutual projection between audience and performer, the identification in which [we] believe so readily in the other as the keeper of our treasure and our disease (Tang, 2004). Valie Export, a similarly omnipresent and provocative figure in the world of art performance, shares the same problems of audience interaction, although not as much as Marina Abramovic. Beside art performance, her repertoire includes film, text, painting and photography to name a few. These avenues of artistic expression gravitate towards her criticisms for feminism and gender. A staunch activist and a progressive performer, she has oftentimes been called a woman living an anachronistic life. This is due to her revolutionary ways to present her ideas that even her colleagues, who without proper notice of her intentions to perform, usually end up dismissing her as too fanciful and idealistic. Her works on ââ¬ËAsemie or the Inability of Expressing Oneself Through Facial Expressionsââ¬â¢ (1973) and ââ¬ËTouch Cinemaââ¬â¢ (1968) garnered both fame and distress. Chief of the reasons that contributed to an admixture of reception from the critics and audience is the fact that her ideas do not create strong meaningful associations that the people can readily identify with. Humor and parody may be part and parcel of her work as a performer, but these effects are not what she contemplated to be so. Indeed, while she wanted to catch the attention of her spectators, her ultimate goal is to instruct them of the subtle messages regarding feminism, modernism and ritual art. Export, along with the controversial artists at the turn of the 21st century, became (in-)famous in the recent decades because of her startling presentations of objects and her body (Mueller, 2004). Of her earlier works, ââ¬ËAktionshose: Genitalpanikââ¬â¢ or ââ¬ËAction Pants: Genitals in Panicââ¬â¢ (1968), Export engaged the audience, piquing their imagination and belief, with a series of photographs, simultaneously permitting them to engage her as the tangible representations of the images presented in the collage. In an art theater in Munich, dressed to the nines, with the crotch cut out of her pants, Valie Export threaded each row person-to-person, showed her outfit thereby giving the film-viewing public with a palpably visual representation with a real female body. In doing so Export tackled the pornographic reduction of women in static representations just when ideas of feminism and gender were starting to develop during that time. Her message is commensurate to a direct, unapologetic, political affront to the abstract objectification of the female body as a fetish. She moved an aesthetic gesture beyond the representational context of the safe boundaries of art into an actual encounter with a public. Export effectively brought to the fore the various dimension of simple, albeit arresting, bodily gestures ââ¬Å"both to produce and to represent action [. . . ] by stressing the moment and the process of its own productionâ⬠(Stiles, n. d. ). Export repudiated the representational static sign and discharged an interventionist act by revealing her yonic-self to the public vis-a-vis the photos on the display. Art performance, in the recent decades since its entrance in the mainstream, has, and is continuing to encompass a wide field of human proclivities which spans across a whole, comprehensive range of emotions, symbols and design. Although traditional views on aesthetics and taste still influence much of the productions in the art, more and more innovative, socially-informed, stunningly beautiful works of art performance are being (re-)invented and (re-)discovered every time. It doesnââ¬â¢t matter whether these newly created art forms subscribe to tradition or to the taste of the general public. What matters most is the never-ending quest to plumb the full extent of our humanity as individuals and as a community. Art performance is yet to supplant, at least equal the popularity of video-films, cinema, photography and painting in terms of the instances that these are demanded by the public. But with the works of Marina Abramovic, Ulay, Damien Hirst, Valie Export et al and their boundless passion to break the mold and stun the public to enlightenment, art performance can be considered as a significant cornucopia of art studies and of artistic expression. A number of critics do give favorable comments to Marina Abramovicââ¬â¢s performances and ingenuity, Valie Exportââ¬â¢s live photography sessions, Hirstââ¬â¢s ââ¬Å"gleaming vitrines with suspended animals insideâ⬠(Freeland, 2001). However, it must be noted that even if the critics find them beautiful and artful still its startling content warrants full attention; nothing short of shallow and pedantic in all respects of praise and criticism. Freeland writes, perhaps disinterestedness has some small and specific role in approaching difficult art by enabling us to try harder to look at and understand something that seems very repugnant to the senses (2001). The workââ¬â¢s content and the artist performing are just as crucial as the theories that surround art performance. It is not so much as merely an arbitrary act done through the caprice of a strange art performer. It is instead, a manifestation of our natural tendencies, our history, our sense of taste and what is beautiful, our entire spirituality and lastly, our consciousness set against the body as a tool to perceive reality. Art performance as practiced by these artists is a celebration of the body and of our community. An excellent performance and performer do more than take the audience to elevated heights, but also give them a sense of being truly and undeniably alive. And such, makes all the difference. References Abramovic, M. (2005). Marina Abramovic: the biography of biographies. New York London: Charta Publishers. Abramovic, M. (1998). Artist body: performances 1969-1998. New York London: Charta Publishers. Freeland, C. (2001). But is it art? : blood and beauty. New York: Oxford University Press, Inc. Mueller, R. (1994). Valie Export: fragments of imagination. Bloomington and Indianapolis: Indiana University Press. Stiles, C. (n. d. ). Aktionshose: genitalpanik (action pants: genital in panic). Retrieved January 15 2008, The Galleries at Moore database. Tang, A. (2005). Gazing at horror: body performance in the wake of mass social trauma. (Masters of Arts program, Rhodes University 2005). .
Monday, October 14, 2019
Crohns Disease And Modulen IBD
Crohns Disease And Modulen IBD Crohns disease and Modulen IBD Crohns disease is a chronic disease associated with inflammations of the digestive tract. However, most often the lower part of the intestine (the ileum) is affected. Crohns disease is characterized by periods of remission and exacerbations. Currently, there is no remedy for Crohns disease; inducing and maintaining remission of disease activity, addressing complications and correcting malnutrition are the most predominant objectives of treatment. Nestles Modulen IBD is especially composed for patients with Crohns disease. Modulen IBD is a casein-based formula that is rich in transforming growth factor-beta (TGF-B2). This nutritionally complete polymeric formula can be given either by the nasogastric route or orally as the sole source of nutrition or as a supplement. According to Nestle, Modulen IBD is suitable for patients over five years of age and can be reconstituted to a variety of caloric densities. Evaluation of Modulen IBD based on evidence in literature Both corticosteroids as enteral nutrition (EN) are used in the treatment of Crohns disease. However, the effectiveness of EN compared to the use of conventional steroids is controversial. Both the effectiveness of exclusive EN therapy as primary therapy to induce remission in Crohns disease as well as the efficacy of EN for the maintenance of remission in Crohns disease are recently evaluated. In a Cochrane meta-analysis of six trails including 192 patients in the EN group and 160 patients in the steroid group, it was concluded that EN can induce remission of active Crohns disease. However, this effect was found to be inferior to steroids. These findings are in line with past meta-analyses. In contrary, it is indicated that the effectiveness of EN diverges between adults and children; two pediatric trials (of which one was an abstract) with a total of 58 patients and a previous meta-analysis with 147 children demonstrated that EN equals the efficacy of steroids in the induction of remission in pediatric Crohns disease. Moreover, no dissimilarities in the effectiveness of elemental nutrition and non-elemental nutrition can be found based on 10 trials including 344 patients. A recent review of Akobeng and Thomas (2007) showed that supplementary EN can be effective for maintenance of remission in Crohns disease. Data is based on two recent randomized clinical trials, however, sample sizes were too small to provide statistical power. Recommendations It is strongly indicated that steroids are more effective in inducing remission in Crohns disease compared to EN. Additionally, compliance might be less for exclusive nutritional intervention compared to the use of steroids; several studies demonstrated a higher withdrawal rate in patients that were treated with EN compared to patients receiving steroids. Nonetheless, the use of steroids as a first line treatment in children should be carefully considered for several reasons. First, it is shown that EN in children is equally effective as steroids in the induction of remission. Moreover, the use of steroids is often associated with side effects in children such as impaired growth and bone mineral density [1; 3]; the use of EN is regarded as safe. A long-term randomized pediatric trial of 37 patients demonstrated that withdrawal rates were comparable in the group of children receiving EN as well as in the group receiving steroid treatment; withdrawal rates in the EN group were even inf erior to those observed in adult studies. Accordingly, it is recommended to use EN to induce clinical remission in the growing child suffering from Crohns disease. Additionally, adults can be treated with EN as an alternative for conventional steroid use if they suffer from intolerances to steroids or if they (strongly) denote to prefer the use of EN above steroids. Since it is suggested that elemental and non-elemental diets are equally effective, it is advisable to treat patients with a polymeric diet such as Modulen IBD since polymeric diets have a higher palatability and compliance is expected to be improved. Although the current evidence suggests that supplementary EN may be effective for maintenance of remission in Crohns disease, evidence is not indisputable and it is indicated that more research is needed to confirm these findings. Furthermore, studies should be performed to elucidate the daily amount of EN required to maintain clinical remission in Crohns disease patients as well as the cost-effectiveness of supplementation as the impact on the quality of life for the patient. Moreover, the compliance of supplementation is expected to be low since the end-point for patients is unclear. In conclusion, EN is advisable in children during a remission to avoid steroid side-effects such as an impaired growth and development. In special cases, Modulen IBD can be prescribed to adults. For the time being, Modulen IBD supplementation for the maintenance of remission is not advised. The additional benefits for mucosal healing, growth, nutritional status and quality of life strengthens the argument for considering its use as primary therapy. Kosten, Compliance. polymeric nutrition is more palatable than elemental nutrition; polymeric diets are less expensive and more palatable than elemental diets, and therefore it would seem reasonable to suggest that there is no place for the elemental diet. Improvement quality of life? Improvement nutritional status? Module ibd is a naturally complete powdered feed, designed to meet the specific nutritional needs of people with Crohns disease. It is free from gluten, lactose and is suitable for vegetarians. EN by means of a polymeric diet can be given via the nasogastric or per oral route. Module IBD is designed for patients with Crohns disease, can be used as the sole source iof nutrition or as an oral supplement. The specific polymeric diet selected was a highly palatable, casein-based formula rich in TGF-B2 (transforming growth factor) which can be taken by mouth. Crohns disease is a chronic inflammatory disease of the intestines. Crohns disease frequently occurs in the lower part of the small intestine (the ileum), however, it can affect any part of the digestive tract, from the mouth tot the anus. Crohns disease is a cgronic relapsing consition with a high morbidity. There is no cure for Crohns disease. Treatment is aomed at inducing and maintaining remission of disease activity, correcting malnutrition, addressing complications, and thereby improving the quality of life of patients. The relative merits of corticosteroids and enteral nutrition in the treatment of Crohns disease remains an area of controversy. There was a cumulative withdrawal rate of 26% in those receiving enteral nutrition compared to zero in the steroid group. .. there was a 39% withdrawal rate in the enteral group compared to only 9% in the steroid group. In the pediatric study, the majority took the feed orally, but if they failed adequate oral consumption, NG feeds were administered (in 23.5% of subjects). The withdrawal rates were similar in both the neteral nutrition (10.5%) as in the steroid arm (11.1%). The mild active subjects were allowed to take the feeds orally, while those with moderate to severe disease received the diet nasogastrically. Although polymeric diets are more palatable, failure can occur if inadequate oral administration occurs, and the nasogastric route should then be used to optimize compliance and effectiveness. Although exclusion of a normal diet/and or the nasogastric route of administration mey be viewed as barriers to enteral nutritional therapy, even young children can learn to insert the tube for overnight feeds. may suggest that the benefits of enteral nutrition differ between adults and children. Although the majority of data suggests that patients treated with corticosteroids more often achieve clinical remission, it is well established that corticosteroids fail to induce mucosal healing. Studies demonstrate a substantial higher drop-out rate for continuing enteral nutritional theraphy, whether given orally or by overnight nasogastric intubation. Enteral nutrition has important growth and developmental benefits and continues to be a recommended therapy for children with Crohns disease. The sample sizes of both included studies were small and the studies lacked statistical power. It is therefore difficult to draw any definite conclusions from these data. Future studies should be well-powered and should also investigate the amount of enteral nutritional supplements that will produce optimal benefits. These studies should also assess cost-effectiveness and the impact of supplementation on patientsquality of life. The optimal daily amount of enteral nutrition that needs to be consumed is unknown. In individual cases, EN can be provided to adults: steroid intolerance, patient refusal of steroids or undernourished individuals. Treatment can take 4-8 weeks, depending on the patients characteristics.
Sunday, October 13, 2019
Electrical Engineering :: Graduate Admissions Essays
Electrical Engineering My decision to pursue graduate study in the United States is underscored by my desire to be a part of the graduate program at your institution. Purdue University offers the flexibility needed for such a vast and rapidly changing field. The research facilities and the faculty at the university are par excellent. Communications is an industry that has changed our lives. In a very short period it has changed the way we have looked at things since centuries. It is one industry that is going to shape our future for centuries to come. Hence my desire to do masters in electrical engineering with communications as my major. My interest in electronics blossomed during my high school years. It was the time when technology had begun to make an impact on the lives of people in India. Hence engineering with electronics as my major was the first choice for my undergraduate studies. Right since the beginning of my undergraduate study electronics is a subject that has fascinated me with its power of applications. The subjects that I have studied include Linear Electronics, Digital Electronics. These laid the foundation for my courses in Electronic Communication & Communication Systems at a later stage. My undergraduate studies already focus on the communications aspect of electronics. A masters degree in electrical engineering with communications as major field is the next logical step. For the past four months I have been working as a project trainee at the Indian Institute for Advanced Electronics. I am working on the design and development of a "PC Controlled Digital Serial Data Generator". This short stint has given me invaluable practical experience. It has given me the confidence to pursue a masters degree and also kindled a desire to do research. During the course of my work at IIAE, I have come across several scientists. Most of them work in different areas of communications. Interactions with them have made me realize the vastness and the scope of communications. My discussions with them convinced me that specializing in communications will suit me very well. The subject of research which interests me very much is spread spectrum communication systems. Coding theory and combinations is another research subject which arouses my curiosity. The subject Communication Theory which I am studying at present introduces these topics in theory.
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